The scope of non-coding RNA includes, but is not limited to, the following subjects:
-Functional studies dealing with identification, structure-function relationships or biological activity of:
small regulatory RNAs (miRNAs, siRNAs and piRNAs) associated with the RNA interference pathway,
small nuclear RNAs, small nucleolar and tRNAs derived small RNAs,
other types of small RNAs, such as those associated with splice junctions and transcription start sites,
long non-coding RNAs, including antisense RNAs, long ‘intergenic’ RNAs, intronic RNAs and ‘enhancer’ RNAs,
other classes of RNAs such as vault RNAs, scaRNAs, circular RNAs, 7SL RNAs, telomeric and centromeric RNAs,
regulatory functions of mRNAs and UTR-derived RNAs,
catalytic and allosteric (riboswitch) RNAs,
viral, transposon and repeat-derived RNAs,
bacterial regulatory RNAs, including CRISPR RNAS.
-Analysis of RNA processing, RNA binding proteins, RNA signaling and RNA interaction pathways:
AGO, PIWI and PIWI-like proteins,
other classes of RNA binding and RNA transport proteins,
RNA interactions with chromatin-modifying complexes,
RNA interactions with DNA and other RNAs,
the role of RNA in the formation and function of specialized subnuclear organelles and other aspects of cell biology,
intercellular and intergenerational RNA signaling,
structure-function relationships in RNA complexes.
-RNA analyses, informatics, tools and technologies:
transcriptomic analyses and technologies,
development of tools and technologies for RNA biology and therapeutics.
-Translational studies involving long and short non-coding RNAs:
identification of biomarkers,
development of new therapies involving microRNAs and other ncRNAs,
clinical studies involving microRNAs and other ncRNAs.